Job Description
About This Role
Biogen is seeking a highly motivated scientist to join the Drug Metabolism and Pharmacokinetics (DMPK) department at our Kendall Square site in Cambridge, Massachusetts. The role requires hands-on experience in conducting in-vivo studies in rodents, and basic familiarity with the concepts of pharmacokinetics (PK). The ideal candidate will not only conduct PK studies in nonclinical models but will also conduct animal surgeries when necessary.
What You'll Do
- Conduct rodent PK studies with diverse modalities such as small molecule compounds, monoclonal antibodies, and gene therapy medicinal products.
- Dosing in mice and rats via the routes including but not limited to IV, PO, SC, IP, IT, and ICV.
- Rodent sample collection including but not limited to plasma, serum, urine, cerebrospinal fluid (CSF), brain, spinal cord, and other tissues
- Interface with Biogen institutional animal care and use committee (IACUC) to write and update experimental protocols
- Additional opportunities for development will be provided such as interacting with CROs, contributing to scientific publications, evaluating emerging in-vivo technologies and interfacing with project teams.
Who You Are
You enjoy performing in vivo studies in rodents, work collaboratively with peers and are motivated to learn novel in vivo techniques and skills.
Qualifications
- BS or MS degree in Pharmaceutical Sciences, Biochemistry, Chemistry, or a related field. BS w/ 2-4 years' experience OR MS w/ 0-2 years' experience.
- Hands-on experience in conducting rodent in-vivo studies on a regular basis.
- Hands-on experience with dosing mice and rats via the routes including but not limited to IV, PO, SC, IP, IT, and ICV.
- Hands-on experience with rodent sample collection including but not limited to plasma, serum, urine, CSF, brain, spinal cord, and other tissues.
Preferred Qualifications
- Experience with non-conventional in vivo PK studies such as studies with bile duct cannulated rats or with portal vein cannulated rats.
- Hands-on experience and expertise in animal surgeries.
Additional Information
Why Biogen?
We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
