Senior Scientist, TCR Gene Therapy

Gaithersburg, MD

Are you passionate about eradicating cancer and highly motivated to explore T-cell receptor (TCR) gene therapy approaches? We are seeking a Senior Scientist to join our Oncology R&D team. This is your chance to work on the next generation of new drug modalities and experience more than traditional molecules.

Accountabilities:

In this role, you will be responsible for developing and leading pipeline tumor-specific TCR-T therapy projects. You will also be tasked with developing strategies to increase antitumor potency of TCR-engineered T cells, critically analyzing and interpreting data, and contributing to study reports and presentations.

Essential Skills/Experience:

PhD or MD in relevant subject area with at least 7 years of experience in immunology
Track record of innovation in TCR-T immunotherapy research
Experience in culturing and expanding human T cells using a variety of methods
Expertise in genetically modifying T cells
Extensive experience in common immunological assays
Great attention to detail
Excellent communication and organizational skills
Highly developed problem-solving skills
Ability to motivate and lead a small team
Ability to drive projects to completion

Desirable Skills/Experience:

Molecular biology skills
Experience in human adoptive cell therapy trials
Expertise in a wide range of gene engineering platforms
Experience in preclinical mouse models of adoptive cell therapy
Experience in cell therapy development in a biotech/pharma setting

At AstraZeneca, we are pioneers, making bold moves that transform the way cancer is treated and truly improve patient outcomes. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate, and work at pace. We lead through true collaboration, building collective wisdom by giving everyone a chance to input. It's science with an impact-making a difference for patients and people around the world.

About Our Gaithersburg Oncology Hub

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.

So, what's next?

Are you ready to push the boundaries of science to change the practice of medicine? Apply now and join us in our mission to eliminate cancer as a cause of death!

If you're curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.

Closing Date: October 30, 2024

Competitive remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

Where can I find out more-

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

The annual base pay (or hourly rate of compensation) for this position ranges from $105,875 to $158,812. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

01-Oct-2024

Closing Date

29-Oct-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.