Job Description

Job Description

At our company, we are inspired by the belief that a research-driven enterprise dedicated to scientific excellence can create medicines and vaccines that save and improve lives. Every employee is building on our proud legacy of scientific breakthrough. Our ability to impact the lives of patients worldwide depends on the integrity, creativity, humility, and scientific acumen of our team. We are creating a diverse organization that is inspired by invention and founded on a culture of respect and collaboration. At our company's Research Labs, you'll have the opportunity to expand your knowledge and skills through collaboration with talented and dedicated colleagues while advancing your career.

Our company is currently seeking passionate synthetic organic or medicinal chemists for positions within the Discovery Chemistry Department located at our West Point, PA site. The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent novel medicines by applying innovative synthetic chemistry, analytical techniques, and data analysis to design and synthesize drug candidates and intermediates.

Successful candidates must have excellent interpersonal, collaboration, and communication skills in a team environment and a proven record of solving complex problems. Additionally, it is expected that the successful candidate will learn quickly through on-the-job training to become increasingly skilled and independent in reaction setup, route design and optimization.

Specific responsibilities will include:

• Collaborative and independent synthetic route design, execution, and optimization to access assigned target molecules using modern synthetic chemistry techniques

• Selection and application of appropriate purification techniques including flash chromatography, high performance liquid chromatography (HPLC) and recrystallization

• Acquisition and interpretation of analytical data such as NMR and LC/MS

• Using available data sets and in silico tools to generate novel, testable hypotheses and target molecules to enable clear decision making

• Participation in the triage and selection of molecules for additional studies (DMPK, in vivo experiments, counter screening etc.)

Education Minimum Requirement:

• Minimum qualifications include B.S. or equivalent degree in chemistry, biochemistry or related field with (3+) years of industrial and/or academic research experience or Master's degree in chemistry, biochemistry or related field (with expected completion no later than May 2025).

Required Experience and Skills:

• Relevant experience must involve the application of organic synthesis

• Experience with independent synthetic route design, execution and optimization using modern synthetic techniques

• Experience with the selection and application of appropriate purification techniques (flash chromatography and HPLC) and analytical data (LC/MS and NMR) to support execution of synthetic routes

Optional skills:

• Knowledge and experience interpreting biological activity data (structure-activity relationships)

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US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

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Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

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Requisition ID:R330192